Vitamin C and Oxidative DNA Damage Revisited
نویسندگان
چکیده
Reactive oxygen metabolites can pro mote carcinogenesis by damaging DNA. vi tamin C is a redox chemical with antioxi dant and pro-oxidant properties that may produce radical species depending on the presence of various conditions. Nevertheless, evidence presented herein discourages the consideration of any mutagenic or carcino genic activity of vitamin C. In contrast, it substantiates a protective and anti carcino genic effect of ascorbate in vivo.
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